What are the three types of TB treatment?

What are the three types of TB treatment?

These are the three treatment options:

  • Isoniazid (INH): This is the most common therapy for latent TB.
  • Rifampin (Rifadin, Rimactane): You take this antibiotic each day for 4 months.
  • Isoniazid and rifapentine: You take both of these antibiotics once a week for 3 months under your doctor’s supervision.

Which medicine is best for TB treatment?

The usual treatment is: 2 antibiotics (isoniazid and rifampicin) for 6 months. 2 additional antibiotics (pyrazinamide and ethambutol) for the first 2 months of the 6-month treatment period.

What is the first drug of choice for tuberculosis?

MDR TB strains can also grow resistant to second-line drugs, further complicating treatment. MDR TB occurs when a Mycobacterium tuberculosis strain is resistant to isoniazid and rifampin, two of the most powerful first-line drugs.

What are the second line drug for tuberculosis?

Second line drugs are the TB drugs that are used for the treatment of drug resistant TB. The second line drugs include levofloxacin, moxifloxacin, bedaquiline, delamanid and linezolid. There is also pretomanid which is a new second line drug recommended in 2019 for the treatment of drug resistant TB.

What is the difference between first-line and second line TB drugs?

The first-line therapeutic drugs are the most effective and least toxic for use in the treatment of TB, while the second-line therapeutic drugs are less effective, more expensive and have higher toxicities. They are however, essential for the treatment of drug resistant forms of the bacteria (MDR-TB).

Why is TB treated with 4 drugs?

Regimens for the treatment of TB disease must contain multiple drugs to which the bacteria are susceptible. The standard of care for initiating treatment of TB disease is four-drug therapy. Treatment with a single drug can lead to the development of a bacterial population resistant to that drug.

What are the third line drugs for TB?

Third line

  • rifabutin.
  • macrolides: e.g., clarithromycin (CLR);
  • linezolid (LZD);
  • thioacetazone (T);
  • thioridazine;
  • arginine;
  • vitamin D;
  • bedaquiline.

What is the difference between first-line and second-line TB drugs?

Why 2nd line drugs are used in TB?

What are the 2 formulations of anti TB drugs?

Currently, the WHO Model List of Essential Drugs includes two-drug formulations (INH + RIF and INH + ethambutol), three-drug formulations (INH + RIF + ethambutol and INH + RIF + pyrazinamide) and a four-drug formulation (INH + RIF + ethambutol + pyrazinamide) [13].

How do you know if TB treatment is working?

After taking TB medicine for several weeks, a doctor will be able to tell TB patients when they are no longer able to spread TB germs to others. Most people with TB disease will need to take TB medicine for at least 6 months to be cured.

Can I take rifampin and isoniazid at the same time?

Rifampin and isoniazid combination is used to treat tuberculosis (TB) infection. It may be taken alone or with one or more other medicines for TB.

Which antibiotic is first active antibiotic for TB?

The first line of inquiry was the development of antibiotics from the first antibiotic (penicillin) to the first antibiotic successfully used to treat tuberculosis (streptomycin) (7, 8).

What medications are used to treat TB?

The following medications are commonly used to treat TB:

  • Isoniazid. Each small white tablet contains 100mg of Isoniazid and the adult dose is 300mg daily.
  • Rifampicin. The capsules come in two strengths,150mg or 300mg. The colours vary with the different brands and strengths.
  • Why should I take antibiotics for TB?

    You cannot spread TB to other people.

  • In some people,the bacteria can become active. If this happens,you may become sick,and you can pass the TB germs to someone else.
  • Even though you do not feel sick,you need to take medicines to treat latent TB for 6 to 9 months.
  • What are the side effects of TB medications?

    Nausea or vomiting

  • Loss of appetite
  • A yellow color to your skin (jaundice)
  • Dark urine
  • Easy bruising or bleeding
  • Blurred vision
  • What is the best medicine for tuberculosis?

    What is the best medication for tuberculosis? Healthcare providers follow a set of guidelines for antibiotic tuberculosis treatment. The first-line TB drugs are isoniazid, rifampin, ethambutol, and pyrazinamide, but other antibiotics may be used based on the bacteria’s drug resistance and the patient’s tolerance to the drugs.