What is Sicilian disease?

Sicilian phlebovirus is a phlebovirus associated with sandfly fever. It is related to the Naples and Toscana viruses, which also cause sandfly fever.

What are the symptoms of sandfly fever?

Sandfly fever is a self-limiting infectious disease which occurs only in humans as a result of sandfly (phlebotomus spp.) bite. It leads to different symptoms including fever, rash, diffuse muscle pain, headache, loss of appetite, nausea and vomiting.

Why do Sicilians get sickle cell?

The consensus is that the gene was introduced into Sicily and Southern Italy from Northern Africa through the trans-Saharan trade routes, or, alternatively, by means of the Greek colonisation, although the introduction of the gene into Sicily during the Muslim invasion cannot be excluded.

How do you treat sandfly bites?

Treatment. Symptomatic treatment, including application of an ice pack and use of an antihistamine, may offer relief from painful bites. Secondary bacterial infection may require the application of antiseptic cream or the use of antibiotics. In severe cases medical advice may be required.

Do sand flies carry diseases?

Sand flies transmit diseases to animals and humans, including a parasitic disease called leishmaniasis. According to the Centers for Disease Control and Prevention (CDC) , leishmaniasis is rare in the United States.

Is thalassemia common in Italians?

Beta thalassemia most often affects people who are of Mediterranean (Greek, Italian and Middle Eastern), Asian, or African descent.

Can sandfly bites make you sick?

In general, sand fly bites are painful and may cause red bumps and blisters. These bumps and blisters can become infected or cause skin inflammation, or dermatitis. Sand flies transmit diseases to animals and humans, including a parasitic disease called leishmaniasis.

What sickness does sandfly cause?

Leishmaniasis is a parasitic disease that is found in parts of the tropics, subtropics, and southern Europe. Leishmaniasis is caused by infection with Leishmania parasites, which are spread by the bite of infected sand flies. There are several different forms of leishmaniasis in people.

How do you treat sand fly bites?

How to treat sandfly bites. Antihistamine tablets or creams can help. Some people also experience relief by applying ice to the bite. Bites should never be scratched as this increases the chance of the wound becoming infected.

What are the main causes of thalassemia?

Thalassemia is caused by mutations in the DNA of cells that make hemoglobin — the substance in red blood cells that carries oxygen throughout your body. The mutations associated with thalassemia are passed from parents to children.

Can sand flies lay eggs in your skin?

The fleas lay eggs through a hole in the skin, and the eggs fall to the ground where they hatch. After about three weeks, the burrowed parasite dies and ceases causing symptoms.

Does sandfly cause malaria?

Among the vectors were mosquitoes, sand flies, biting midges, bat flies, black flies, fleas, kissing bugs and ticks. They carry a cornucopia of microorganisms that today cause diseases such as filariasis, sleeping sickness, river blindness, typhus, Lyme disease and, perhaps most significantly, malaria.

What are the different types of sialic acid storage disease?

People with sialic acid storage disease have signs and symptoms that may vary widely in severity. This disorder is generally classified into one of three forms: infantile free sialic acid storage disease, Salla disease, and intermediate severe Salla disease. Infantile free sialic acid storage disease (ISSD) is the most severe form of this disorder.

How is a diagnosis of sialidosis made?

A diagnosis of sialidosis is made based upon identification of characteristic symptoms, a detailed patient history, a thorough clinical evaluation and a variety of specialized tests. An examination of urine may reveal increased levels of oligosaccharides.

What are the two types of sialidosis?

Sialidosis is divided into two types (i.e., type I and type II). Sialidosis type I usually becomes apparent during the second decade of life with the development of sudden involuntary muscle contractions (myoclonus), distinctive red spots (cherry-red macules) in the eyes, and sometimes additional neurological findings.