What is translational research bench to bedside?

What is translational research bench to bedside?

The term “Bench to Bedside” is used to describe the process by which the results of research done in the laboratory are directly used to develop new ways to treat patients, according to the National Cancer Institute (NCI) dictionary.

Is the Journal of Translational Medicine legitimate?

The Journal of Translational Medicine is a peer-reviewed open-access medical journal published by BioMed Central since 2003. The editor-in-chief is Francesco Marincola. According to Journal Citation Reports, the journal has a 2017 impact factor of 4.197.

Why is bench to bedside important?

Finding ways to prevent the initial development or recurrence of a disease or condition. These can include medicines, vaccines, or lifestyle changes, among other approaches. Evaluating one or more interventions aimed at identifying or diagnosing a particular disease or condition.

How long is bench to bedside?

10 to 15 years
Timeframe. There is no exact timeline for moving something from bench to bedside, and, although it typically takes anywhere from 10 to 15 years, it can be highly variable.

What is meant by bench research?

Bench research: Basic scientific discovery conducted literally at a laboratory bench – think pipetting, running gels, biochemistry experiments, etc. This is type of research is usually directed at finding out one particular piece of a scientific puzzle.

What is a bench research study?

All scientific research conducted at medical schools and teaching hospitals ultimately aims to improve health and ability. Basic science research—often called fundamental or bench research—provides the foundation of knowledge for the applied science that follows.

Is journal of translational science peer reviewed?

Journal of Translational Science (JTS) is an open access journal with comprehensive peer review policy and a rapid publication process.

Why does it take so long to bring a new therapeutic from the benchtop to the market place?

This is due to the extremely rigorous regulations that the Food and Drug Administration (FDA) enforce to ensure that drugs are safe and effective. What follows are the general phases of drug development and the hurdles that must be crossed in each before moving forward.

What is a translational model?

The Translational Science Benefits Model is intended to provide benchmarks to assess the impact of research that applies scientific findings to enhance public health and well-being. A paper explaining the development of the tool was published September 8, 2017 in Clinical and Translational Science.

What does bench side mean?

Definition of side bench : the seat along the side of a small boat especially : the fore-and-aft planking over the air tanks in a small boat fitted with air tanks that is available as a seat.

What is bench research vs clinical research?

Clinical research includes looking at patient outcomes and clinical trials. Translational research is supposed to be bench research that is directly relatable to patients and is often referred to as ‘bench to bedside’ research. This is probably the most vague as it encompasses both bench and clinical research.

What are the three types of biomedical research?

Results. Three main areas of medical research can be distinguished by study type: basic (experimental), clinical, and epidemiological research. Furthermore, clinical and epidemiological studies can be further subclassified as either interventional or noninterventional.

What are the two areas of focus for translational research?

Translational research includes two areas of translation. One is the process of applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans.

What is bench-to-bedside?

It is also commonly referred to as bench-to-bedside, i.e. laboratory to clinic. The development of novel treatments, procedures, and technologies relies on tapping the wealth of knowledge that resides in the silos of basic sciences.

What is bench to bedside cancer treatment?

The term “Bench to Bedside” is used to describe the process by which the results of research done in the laboratory are directly used to develop new ways to treat patients, according to the National Cancer Institute (NCI) dictionary. This term is not new.

What is translational research and how does it work?

This application of basic science to clinic is called translational research. It is also commonly referred to as bench-to-bedside, i.e. laboratory to clinic. The development of novel treatments, procedures, and technologies relies on tapping the wealth of knowledge that resides in the silos of basic sciences.