What kind of drug is zolazepam?

What kind of drug is zolazepam?

Zolazepam is a pyrazolodiazepinone derivative used as an anaesthetic in veterinary medicine. Zolazepam is typically used in combination with the NMDA antagonist tiletamine or the α2 adrenoceptor agonist xylazine.

Is zolazepam a controlled substance?

Zolazepam is part of a proprietary mixture (Telazol; distributed by Zoetis, Kalamazoo, Michigan; Made in Spain) and is not readily available as a single agent. Diazepam and midazolam are both controlled substances and subject to appropriate controlled-drug handling, as are the opioid drugs.

What is tiletamine-zolazepam used for?

Tiletamine-zolazepam can be administered for sedation or anesthesia of short-to-moderate duration or for induction before gaseous anesthesia. Separately tiletamine and zolazepam do not have ideal sedative or anesthetic properties but together they produce dissociative anesthesia, muscle relaxation and some analgesia.

What is Telazol used for?

Commonly known as Telazol®, it is used in dogs and cats as a restraint, anesthesia and sedation. Tiletamine belongs to a class of drugs known as dissociative hypnotics, and is similar to phencyclidine (PCP).

What drug is used to sedate animals?

Background: Telazol (tiletamine hydrochloride 50 mg/mL, zolazepam hydrochloride 50 mg/mL) is utilized in veterinary medicine as a small-animal anesthetic. Telazol is comparable to ketamine in efficacy, and in conjunction with ketamine, has been responsible for one reported human fatality.

Is tiletamine-zolazepam a dissociative drug?

ACTIONS: Tiletamine-Zolazepam is a rapid-acting anesthetic combination of tiletamine hydrochloride and zolazepam hydrochloride. Tiletamine hydrochloride is a dissociative anesthetic agent whose pharmacologic action is characterized by profound analgesia, normal pharyngeal-laryngeal reflexes and cataleptoid anesthesia.

What is Kitty Magic anesthesia?

Many US veterinary practices have adopted “Kitty Magic” as the feline anesthesia/analgesia protocol of choice as it. combines premedication, induction, some general anesthesia, and postoperative analgesia into a single IM injection.

What schedule is butalbital?

Currently, products that contain butalbital/aspirin/caffeine are classified as schedule III controlled substances; butalbital products listed on the DEA’s list of Exempted Prescription Products, including butalbital/acetaminophen/caffeine products, are unscheduled.

Is tiletamine zolazepam a dissociative drug?

Is tiletamine a controlled substance?

Tiletamine products are classified as Schedule III controlled substances in the United States.

How long is Telazol good for?

A: TELAZOL should be stored at controlled room temperature 20° to 25°C (68° to 77°F) prior to use. After initial use, discard unused solution after 7 days when stored at room temperature or after 56 days when kept refrigerated.

Is Telazol used in humans?

An equal-dose combination of tiletamine and zolazepam (Telazol®) is used as a veterinary anesthetic. There also have been reports of human abuse of Telazol®. The pharmacokinetics and metabolic fate of tiletamine and zolazepam and the rationale for their administration as an equal-dose combination are unclear.

What class of drug is tiletamine?

Tiletamine is a non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist chemically related to ketamine and phencyclidine. A common veterinary anesthetic drug, tiletamine is currently a Schedule III controlled substance in USA.

What is Kitty Magic made of?

Knumina Studios/Shutterstock.com“Kitty magic, a cocktail of dexmedetomidine, ketamine and butorphanol, is something that people are using in practice a lot. But I think it’s important to note that kitty magic sometimes gets a bad rap,” says CVC educator Tasha McNerney BS, CVT, CVPP, VTS (anesthesia and analgesia).

What will relax my cat?

The 10 Healthiest Ways to Relax With Your Cat

  1. Remind Her Of Kittenhood. When cats are tiny kittens, their mother uses licking as a way to clean and soothe them.
  2. Give Him A Massage.
  3. Play With Them!
  4. Give ‘Em The Nip.
  5. Cuddle Time.
  6. Everyone Loves A Good Treat!
  7. Grow A Cat Garden.
  8. Listen To Music Together.

Is Telazol a controlled substance?

A: Yes, TELAZOL is a Class III DEA controlled substance. As such, it is necessary to provide special shipping and storage, and to ensure accurate record keeping. Since this is a controlled substance, the Zoetis field force cannot take possession of this product.

How is zolazepam administered with other medications?

Zolazepam is usually administered in combination with other drugs such as the NMDA antagonist tiletamine or the α2 adrenergic receptor agonist xylazine, depending on what purpose it is being used for.

What is zolazepam and tiletamine hydrochloride?

ACTIONS: Tiletamine-Zolazepam is a rapid-acting anesthetic combination of tiletamine hydrochloride and zolazepam hydrochloride. Tiletamine hydrochloride is a dissociative anesthetic agent whose pharmacologic action is characterized by profound analgesia, normal pharyngeal-laryngeal reflexes and cataleptoid anesthesia.

What is the history of zolazepam?

Zolazepam was developed by Horace A. de Wald and Donald E. Butler for Parke-Davis and was the result of a very detailed analysis of the benzodiazepine structure ( U.S. Patent 3,558,605 filed in 1969).

What is the difference between zolazepam and flumezenil?

Zolazepam is avaiable only in combination with tiletamine, marketed as Telazol ®. Flumezenil, a specific benzodiazepine antagonist, is used as a reversal agent for benzodiazepines in the event of an overdose, or to hasten recovery.

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