What are the symptoms of severe vitamin B12 deficiency?

Vitamin B12 or folate deficiency anaemia can cause a wide range of symptoms. These usually develop gradually, but can worsen if the condition goes untreated.

• extreme tiredness (fatigue)
• lack of energy (lethargy)
• breathlessness.
• feeling faint.
• headaches.
• pale skin.
• noticeable heartbeats (palpitations)

Can isotretinoin cause B12 deficiency?

After 6 months on isotretinoin, the acne patients experienced a statistically significant decrease in vitamin B12 and folic acid levels. Vitamin B12 deficiency was more commonly identified and more likely to be symptomatic in patients undergoing more than one 6-month course of treatment.

Can I take vitamin B12 with isotretinoin?

No interactions were found between isotretinoin and Vitamin B12. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Does lack of B12 cause acne?

Li and her team found that taking vitamin B12 increases the amount of that vitamin on facial skin. This, in turn, causes a certain facial bacteria (propionibacterium acnes) to produce more of something called porphyrins, which results in inflammation. And this could lead to acne.

Can lack of B12 cause acne?

A Vitamin B deficiency can wreak havoc on your skin, causing acne, rashes, dry and flaky skin, cracked lips, and wrinkles.

Can low B12 cause wrinkles?

Does B12 darken skin?

The hyperpigmentation related to vitamin B12 deficiency is more common in darker-skinned patients. Few other cases of skin hyperpigmentation due to vitamin B12 deficiency have been reported in the literature. The mechanism of hyperpigmentation is due to increased melanin synthesis rather than a defect in melanin.

Does B12 affect sleep?

A lot of research has been done on how Vitamin B12 both directly and indirectly affects sleep. It has been found that the vitamin works directly on the brain to help induce sleep. Vitamin B12 benefits have been demonstrated to help patients with sleep disorders, such as insomnia, who have difficulty falling asleep.