What is SAMe supplement good for?

What is SAMe supplement good for?

More like a vitamin than a drug, SAM-e is a natural metabolite that the body needs more of as we age or if we become ill. SAM-e is generally safe and evidence-based for the treatment of depression. It is also a promising neuroprotectant and may be helpful in treating ADHD.

How long does it take SAMe to start working?

“Starting patients with 200 mg 30 minutes before breakfast and 30 minutes before lunch minimizes the overstimulation and insomnia which some patients report in the first few weeks. This can be switched to 400 mg before breakfast after a few weeks.” Patients typically notice improvement in energy within two weeks.

Does SAMe help with anxiety?

SAMe is used by mouth for depression, anxiety, heart disease, fibromyalgia, abdominal pain, osteoarthritis, bursitis, tendonitis, chronic lower back pain, dementia, Alzheimer’s disease, slowing the aging process, chronic fatigue syndrome (CFS), improving mental performance, liver disease, and Parkinson’s disease.

Can you take SAMe long term?

Information on the long-term safety of SAMe is limited because the participants in most studies took it only for short periods of time. However, in one study of alcohol-related liver disease, participants took SAMe for 2 years; in that study, no serious side effects were reported.

What are the side effects of taking SAMe?

Side effects might include gas, diarrhea, constipation, dry mouth, headache, and nervousness, especially at higher doses. Pregnancy and breast-feeding: There isn’t enough reliable information to know if SAMe is safe to use when pregnant or breast-feeding. Stay on the safe side and avoid use.

What is the best time of day to take SAMe?

SAM-e should be taken on an empty stomach. It can be stimulating, so it’s best to take it early in the day so it doesn’t disrupt your sleep.

What are the side effects of SAMe?

SAMe can cause:

  • Digestive problems, such as nausea, diarrhea or constipation.
  • Mild insomnia.
  • Dizziness.
  • Irritability.
  • Anxiety.
  • Sweating.

How long can I take SAMe?

Dosing. SAMe has most often been used by adults in doses of 400-1600 mg by mouth daily for up to 12 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Does SAMe affect blood pressure?

SAM may affect the nervous control of arterial blood pressure via the autonomic nervous system and KATP channel-dependent mechanisms.

How long can you take SAMe?

SAMe has most often been used by adults in doses of 400-1600 mg by mouth daily for up to 12 weeks. Speak with a healthcare provider to find out what dose might be best for a specific condition.

Does SAMe have to be taken on an empty stomach?

SAM-e Sources and Dosage SAM-e should be taken on an empty stomach. It can be stimulating, so it’s best to take it early in the day so it doesn’t disrupt your sleep.

Does SAMe work for joint pain?

Their conclusions were interesting. SAMe was not more effective at relieving pain than a placebo. However, compared to NSAIDs for the treatment of osteoarthritis, the supplement was found to be just as effective in reducing pain and improving joint function — and was less likely to cause the side effects of NSAIDs.

How do I wean off SAMe?

You might be able to cut the pill in half to start off at a lower dose. I did begin taking the 200mg in the morning, with an empty stomach. After taking this dosage daily for several weeks then I upped it to two pills at 200 mg each twice a day.

Can SAMe affect the heart?

SAMe may interact with antidepressant medications, increasing the potential for side effects including headache, irregular or accelerated heart rate, anxiety, and restlessness, as well as the potential fatal condition called Serotonin Syndrome, mentioned above.

What is the best time to take SAMe?

Can SAMe raise your blood pressure?

Examples of antidepressants that can raise your blood pressure are: Monoamine oxidase inhibitors. Tricyclic antidepressants. Fluoxetine (Prozac, Sarafem)

What vitamins are in Sam E?

The brain synthesizes SAM-e, or s-adenosylmethionine, from methionine, an essential amino acid that plays an important role in the growth of new blood vessels, and adenosine triphosphate, an energy-producing compound that acts as a source of fuel within our cells.

What are the health benefits of Sam E?

Depression. While research has shown that SAMe has a positive effect in treating depression,most studies weren’t well designed and included a small number of people.

  • Liver disease. More studies are needed to determine whether SAMe is beneficial for people who have liver disease.
  • Osteoarthritis.
  • What is Sam-E used for?

    SAM-e has also been used to treat depression for many years. Some studies have found that SAM-e might work as well as tricyclic antidepressants in relieving symptoms. However, many of these studies were flawed or too small to be conclusive. Other uses of SAM-e have not been studied as thoroughly.

    What are the benefits of Sam E?

    Data on the long-term safety of SAMe and its safety for use during pregnancy are too limited to draw any conclusions.

  • SAMe may not be safe for people with bipolar disorder.
  • SAMe may interact with some medicines or other dietary supplements.